The B5 New Acne Cure - Pantethine
90Try The New Acne Cure - Experimented For Years
What if you get rid of your acne 2 days from now? No topical applications, no unknown remedies, no toxic drugs, and no overdose supplements. You will just fine tune the supplements you may be already taking.
After the tremendous response to my hub about facial masks, I decided to give you more of my experience as a pharmacist. Today I will present to you the best successful, experimented cure of acne that I have been recommending people for years. It is based on the brilliant basics of biochemistry and supported by recent scientific findings.
The recommended regimen here is aimed at relieving symptoms of acne, it is to be used temporarily and for a short time. Long term use of high doses of these supplements may induce side effects, and some of them may be serious. If you plan to use them for a long period consult your doctor.
12 Years Boys Have No Acne
Children are free from acne until puberty, when all the body activities
are directed towards building more bones and muscles, and preparing the body to reproduce (to preserve life).The pituitary gland (maestro gland) hormones direct the body to serve these purposes, thus :
• Growth hormone increases utilization of fats for energy production, increases lipolysis (fat breakdown by fat cells), spares carbohydrate, and increases protein synthesis.
• Thyroid Stimulating Hormone(TSH) stimulates the thyroid gland to secrete Thyroid hormones, and these increase oxygen utilization and metabolic rate, as well as they increase glucose absorption.
• Follicle Stimulating Hormone (FSH) and Lutenizing Hormone (LH) causes
increased bio-synthesis of sex steroids by the ovaries and testis. Sex hormones build muscles and raises blood glucose so as to be maintained within a certain range.
The net result is increased energy production from fats, decreased energy production from carbohydrates (as it is needed for protein metabolism) , increased protein synthesis, and increased bio-synthesis of sex hormones. The biochemical translation of that is, the production of huge amounts of COENZYME A.
Acne Cure Supplements
Coenzyme A and Acne
Coenzyme A is the central molecule in our metabolism, it combines acetate that comes from carbohydrates, protein, and fat metabolism to form Acetyl-Coenzyme A, the only molecule that the mitochondria use to produce energy through Krebs cycle. Also fat synthesis - including steroidal hormones - starts with Acetyl Coenzyme A. Acetyl choline the neurotransmitter of all para-sympathetic nervous system can not be synthesized without acetyl-coenzyme A.
Coenzyme A is formed by stepwise union of Cysteine (amino acid), ATP
(high energy molecule), and Pantothenate (Vitamin B5). ATP is provided by metabolism, Cysteine if not present in food can be derived from Methionine (amino acid), and Vitamin B5 can be only provided by food.
The body deals with the high demand of an essential nutrient in such a way to maintain the functionally more important reactions, while at the same time slowing down the less important ones (or why a certain disease is debilitating?).
In our case, where Coenzyme A is a pivotal molecule in at least 70 metabolic pathways, the body chooses to utilize Coenzyme A and excess fats to build sex hormones, leaving excess fats unprocessed and stored. Were there extra amounts of Coenzyme A, the body would metabolize the excess fat in the sebaceous glands.
Now we can easily understand that acne is due to un-metabolized fat that is accumulated in the sebaceous glands, due to insufficient amounts of Coenzyme A,i.e., acne is due to slow metabolism of excess fat.
How to Get Rid of Acne Overnight and Forever
- How To Get Rid of Acne Overnight and Forever: Waheed Elqalatawy: Amazon.com: Kindle Store
How To Get Rid of Acne Overnight and Forever: Waheed Elqalatawy: Amazon.com: Kindle Store
Why It Is Hormones Biosynthesis and Not Androgen Effect
The reason acne first erupts at puberty is not effects of hormones, but rather metabolic, it is secondary to deployement of a substantial amount of coenzyme A to the purpose of synthesis of sex hormones. In the following examples we may see that, it is not the androgen that is the cause of acne:
• Eunuchs (early castrated males) rarely exhibit acne, while normal adult males may exhibit adult acne
• Two groups of adolescent boys with the normal blood levels of androgens may exihibit differnt incidence of acne
• Stress related acne ( prior to examination, tension, insomnia...etc)
is caused by increased synthesis of corticosteroids that the body secretes to combat stress. The same thing apply for adult acne of people who have not had acne as teenagers
• The premenstrual flare of acne patients due to increased levels of progesterone which is not an androgen
• Rapid decline in incidence of acne after puberty is due to cessation of need of increased sex hormones synthesis
• Biotin and Nicotinamide are important vitamins of lipid metabolism, and with vitamin B5 they may help cure acne, yet when they are used alone, they are far less effective in treating acne
• Frequently seen acne with those secreting tumors of the ovary, testis and adrenals, in people with variant ages
Excess Fat
Acne Cure With Coenzyme A
The precursors of coenzyme A are ATP which is very abundant in the body of adolescent people, Cysteine which is non essential amino acid that can be supplied with food or derived from the essential amino acid Methionine, and Vitamin B5 (Pantothenic acid) which is essentially supplied by food.
Pantothenic acid (vitamin B5) supply to increase body production of coenzyme A , has been recommended by Dr Lit-Hung Leung in high doses reaching 1000-1500 times its recommended daily intake which is 10 milligrams per day. The recommended dose is so high (10-15 grams/day), because vitamin B5 is a water soluble vitamin, i.e., with each heart beat the unused B5 molecules pass into the kidney to be excreted. It follows that Vitamin B5 should be present all the time to capture any free Cysteine.
Add Cysteine to Reduce Pantothenic Dose
Since the demand for coenzyme A increases in adolescence, the need for Cysteine must increase. Cysteine is a sulfur amino acid that is heavily used in building keratin, which is an important constituent of the skin (which increases largely in size during adolescence), growing wanted and unwanted hair, and also used in forming nails.
Cysteine free pool in the liver has a narrow range, since the liver cells tightly regulates it to keep it within that range. The liver synthesises Glutathione as a reservoir of cysteine. Glutathione is the primary tool of the liver for detixification. It has a vital role in many cell cycle related events that are needed during tissue repair. It is also vital for maintaining functioning of the immune system.
Cysteine with Glutamic acid (another amino acid) are considered by some researchers to be essential elements for adolescents.
Administration of Cysteine is the only means by which we can reduce the dose of Pantothenic acid. I have recommended the combination of Pantothenic acid + Cysteine for many acne patients for more than 10 years with great results in curing acne.
Taking 0.5-1 grams of Cysteine per day reduces your intake of Pantothenic acid to only 1-1.5 grams per day (they will be combined).
Pantethine, The New Relief
The metabolic pathway of synthesis of coenzyme A involves a compound called Pantetheine which is the direct precursor of coenzyme A. It is now produced in the stable form pantethine, as it involves 2 molecules in the disulfide form of pantethine. It has an extra advantage of being sustained over time, since every molecule has to be split first, and this delays its elimination.
It was intensively researched for its cholesterol and lipid lowering properties (aren't they excess fats?), and has become very popular for cardiovascular support. The literature about Pantethine is full of details about that property, and this made me reluctant to recommend its use for acne, until I found some people are already using Pantethine to cure acne as you can read in the link below.
The dose of Pantethine in most human studies is 900 mg per day and this may be a good guide for us to start with 300 mg three times daily until improvement, it is supposed to improve acne within 2 days.
Read About People Using Pantethine for Acne
- Acne.org Message Boards - Pantothenic vs. Pantethine?
Forum discussion between people using Pantothenic acid and others using Pantethine. Use Message boards link and type in "Pantothenic vs.Panthine"
It is Time To Start
In the below link, there is the details of each product you may choose to cure acne. I included both systems of treatments to overcome the problem of individual variations, so that you may choose the most convenient one that meets your requirements.
If you like take some adjuvants, you may take supplements that contain
Chromium, Zinc, Vitamin E, Vitamin B complex, and Vitamin A, but it is not a must.
Acne Cure Supplements
- Acne Supplements
Go through the details of each item and do not forget that pantothenic acid is combined with Cysteine (1 capsule of each 2-3 times daily). Only Pantethine is taken alone (1 capsule 3 times daily).
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Comments or QuestionsLoading...
Want to exchange links between our two acne hubs?
First, great blog, i know the b5 works i used it a lot. Now i am very curious if i can do it without the 10 grams i took.
After reading all this, this is my plan.
3 times a day Panthetine 300mg, carnitine 200 mg, b5 500 mg and cysteine 500 mg
So i take all paths.
My question is: When shall i take this with or without meal?
The reason i ask this is that i know that amino acid will compete with each other. But the b5 only worked with me when i took it with a meal. But i want the b5 to catch the cysteine off course.
Excuse my English it is not my language..
Thanks for the great peace of writing in this blog!
First, great blog, i know the b5 works i used it a lot. Now i am very curious if i can do it without the 10 grams i took.
After reading all this, this is my plan.
3 times a day Panthetine 300mg, carnitine 200 mg, b5 500 mg and cysteine 500 mg
So i take all paths.
My question is: When shall i take this with or without meal?
The reason i ask this is that i know that amino acid will compete with each other. But the b5 only worked with me when i took it with a meal. But i want the b5 to catch the cysteine off course.
Excuse my English it is not my language..
Thanks for the great peace of writing in this blog!
Instead of using alot of money in trying to cure acne, i would prefer that one tries all the natural methods, that are expense free in avoiding acne. Here are some of the methods that can help you keep off these.
Cloth; You should avoid garments made exclusively of Lycra and nylon if you are prone to body acne since some synthetic fabrics can strap the heat and moisture against your skin. This creates a fertile breeding ground for the bacteria that contribute to acne
For moderate exercise, use light weight, loose fitting cotton or a lycra-cotton blend. Natural fabrics allow the skin to breath and loose garments are less likely to cause friction. If you exercise vigorously and work up a good sweat, try some of the new fabrics designed to wink moisture away from your skin.
Say no to alcohol; if you use a toner avoid products with high concentration of isopropyl alcohol, or common alcohol. A strong astringent alcohol strips the top layer of your skin causing your sebaceous glands to produce more oils resulting to dry red skin and possibly more blemishes.
Hello
Could u please tell me what would be the most important supplements to take for acne, out of those which you have mentioned.
Many Thanks
John Hooks
Hello
Could u please tell me what would be the most important supplements to take for acne, out of those which you have mentioned.
Many Thanks
James
I've been taking Jarrow Formulas Pantethine 450mg two times a day for three weeks now. Haven't noticed any significant change to my acne. No cure within two days. Going to finish the bottle since i paid 23 dollars for it.I'm 5'5.5 and 146 pounds. Do you think i should be taking over 1,000mg a day and how much should you suggest is the amount needed to metabolize more fats in order to get a substantial difference in my acne. Is taking 1800mg a day too much?!
For a majority of people Pantethine works better than PA. Pantethine is the biologically active form of PA and has been seen to offer more benefits than PA.
Good info!
Hi do you have to take anything with pantethine for it to work like cysteine or b complex? And can a small dose be jus as effective to someone who gets regular few spots not full on acne? Overall is it more effective then PA as it seems easier as its less pills
What do you thinks better to take as ive bought both incase one dont work i can try the other pantothine sounds easier but dont no how effective they both are compared to each other
Do they have to be taken after/ with food or does this not make a difference?
Firstly great article thanks for compiling it.
I have been reading about the internet and there seems to be quite a few cases where people achieve better results using pantothenic acid in 10g doses as appose to taking approximatley 750mg of pantethine three times a day.
I have moderate acne and have never tried this type of treatment before, i want to give this treatment a go; so which should I start with pantethine or pantothenic acid???
Hello Mr elqalatawy,
Thank you for this information!
I would like to ask you a question regarding methionine: You said that cysteine is derived from methionine, so if one would like to take methionine instead of cysteine, what quantity of methionine will be required in order to produce the recommended 1-1.5 grams of cysteine daily?
Thank you in advance!
L-cysteine or N-Acetyl-Cysteine? Thank you
Why is not better N-Acetyl-Cysteine than L-Cysteine? N-Acetyl-Cysteine (NAC) has all the properties of L-Cysteine but is more water soluble and said to be more bio-available than L-Cysteine.
diga adeus ao acne
I have read on various websites that Coenzyme A is synthesized within the body by three precursor chemicals (pantothenic acid, cysteine, and ATP -Adenosine-5'-triphosphate). Even if we take pantethine instead of pantothenic acid, why would we not also want to supplement with cysteine?
Marvellous job for the valuable information.
Hi elqalatawy,
I used your advice and I'm taking 500mg L-Methionine and 500mg B5 two times a day. It does reduce sebum and acne, although I don't have a lot of acne anymore (I had it bad when I was younger). I just wanted to report that it works and to thank you again for your site!
Pantothenic acid and hairloss.
If you search the net, there are a lot of people complaining of hairloss when taking large doses of pantothenic acid. There are quite a few theories:
1) Pantothenic acid lowers Biotin causing hairloss
2) Pantothenic acid lowers cysteine causing hairloss
3) Pantothenic acid raises DHT levels causing hairloss
4) Pantothenic acid decreases pore size causing hairloss
There are enough people reporting it, that it has me concerned. Please comment on the following:
1) Why does Pantothenic acid especially in large doses cause hairloss?
2) What can be done to prevent pantothenic acid from causing hairloss?
Thank you!
will there be any rebound reaction after stopping pantethine? thanks
hello, may i know will there be or any reported case of rebound effect after stoppig pantethine?
is it more effective to take pantethine or is it more effective to take pantothenic acid and cysteine?
with pantethine, can you take 2 300mg pills in the morning and one at night or does it have to be spread out throughout the day?
what do you think about combining pantothenic acid with pantethine? I have read several places that it is most effective this way!
I tried pantethine for 1.5-2 months. I can't say that it made that much of a difference in my skin or in my oil production. Should I increase the pantethine? How much can I safely take?
Thank you!
Thank you for the response back. I am currently taking 900 mg of the pantethine in three divided doses. I am willing to give the Methionine a try. However, I thought that if you are taking patethine you do not need Cysteine or Methionine. Please explain.
Thank you!
In addition to taking the Methionine. I was thinking about adding L-Carnitine. Supposedly it helps transport fatty acids across the mitochondrial membrane where they can be oxidized. In theory it reduces the amount of b-5 you have to take. For more information see - http://jeffreydach.com/2008/09/04/pantethenic-acid
What do you think?
Thanks again for the response. OK I am trying the Methionine (1,000mg) + Pantethine (900mg). To get the maximum oil/sebum reduction, do you think I should add some L-Carnitine? If so, how much?
Thanks for all your help!
From what I understand Pantethine turns into Coenzyme A. Coenzyme A is responsible for oxidizing or burning up fatty acids which in turn reduce oil or sebum on the skin. L-Carnitine is a transporter of fatty acids. It transports fatty acids to be burned up as energy. As an analogy. Coenzyme A is the furnace that burns up fatty acids. Carnitine is the delivery truck that brings fatty acids to the furnace.
Doesn't it make sense to take both of them?
Thanks!
Your article says to take the pills (Pantothenic acid and Cysteine)temporarily and for a short time. How long would you recommend taking them for then. I was thinking 2 weeks on one week off.
Thanks
Hi,
thank you very much for your enlightening posting. As in my country Europe Pantethine is not sold as medicine, I only use Pantothenic Acid and L-Cysteine. My skin is getting better with 1,5g PA and 1g L-Cysteine. As I use this regimen for less than a month, I wonder whether it will be getting better even without Pantethine.
Thank you for your reply.
Yours sincerely,
David
Hi,
I have been reading up on pantothenic acid and pantothine. I will be starting one of them but have been getting mixed reviews. I read that Pantothenic acid and Pantothine have different effectts. Im just abit confused on which one would be best to consume? Is there any difference between them??
Regards,
Maj
Hi,
Thank you for your responce. I have purchased jarrow formulas pantethine 450mg. Do I stick to the normal dosage of 900mg a day for acne? I have tryed everything and very frustrated at this moment as nothing is working. Also I take actyl L carnitine on the days I go gym as it is also meant boost your energy levels and use up the stored fat (I hope this is correct). But have been noticing more spots than usual, does this mean that I should stop taking this? Or is this just an initial breakout as I also heard it helps with acne.
Thank you for your time, I look forward from hearing from you.
Regards,
Maj
Hi,
Looks like hr had good results only he was not taking pantethine but patothenic acid with cycsteine, Has anybody ever had improvements with pantethine instead of using pantothenic acid?
Regards,
Maj
Hi elqalatawy,
I was reading up on pantethine as discovered a post;
'pantothene is used for different purposes than pantothenic acid. it's main use seems to be for helping the body burn energy quicker thus lowering the level of cholesterol in the body. So it is mainly used by people with high choleterol. Pantothenic acid does nothing to the bodies cholesterol levels so cannot be used for this purpose. Also pantothene has shown no signs of lowering sebacous gland production in the body. So no pantothene is really no use for acne or oily skin problems.'
I have just purchased pantethine and after reading this and other posts regarding pantethine it has made me begin to think maybe i should use pantothenic acid instead??? Please could you elaborate on this matter for me?
I look forward to hearing from you.
Regards,
Maj
Hi,
Really sorry for annoying you again I just have few more questions.
I am on my third day of taking pantethine and I am taking 450mg twice a day.
Is it recommended to take more than 900mg of Pantethine?? or should I stick to 900mg?
Also I have ordered Pantothenic Acid which I am planing to take 500mg once a day inbetween my Pantethine doses. Would this be ok??
How long does it take to see results??
Thank you for your time.
Kind Regards,
Maj
Hi,
I have been reading 'jhwilso1' posts and it seemed that PA and Cystien worked better for him. But after reading so much of the post all the questions have confused me as I am completely new to all of these vitamins.
I hope you can shed some light here.
I am currently taking 450mg of Pantethine twice a day and I am thinking of taking an extra which makes it 3 x 450.
After only 3 days my skin feels tight and dry im not too sure if this is the Pantethine working. Skin seems to look somewhat clearer but still have a few spots on my forehead and cheeks.
I have ordered vit b5 which I plan to take 1 x 500mg a day, Will I need b Complex vitamins??
You said that ATP is present in people upto the age 20 (i think) I am 24 so does this mean I need to supplement with ATP? What about Cystien? If my body has not produced enough Cystien does this also mean Pantethine will not be effective?
I look forward from hearing from you.
Regards,
Maj
I would really like to thank you for being very helpful.
I really hope this works for my self as well as anybody else who is trying this.
Regards,
Maj
Hi,
I have a concern on pantethine.. I have been taking 450mg 3 times a day... On day 4 my skin now looks worse as im geting spots everywhere on my face.
Should I stop the regimen? My body may not be reacting to this treatment as it should be. Or is this normal? My skin looks much worse than it has previously.
I await your response.
Regards,
Maj
Hi,
I have a concern on pantethine.. I have been taking 450mg 3 times a day... On day 4 my skin now looks worse as im geting spots everywhere on my face.
Should I stop the regimen? My body may not be reacting to this treatment as it should be. Or is this normal? My skin looks much worse than it has previously.
I await your response.
Regards,
Maj
Hi,
I am currently waiting for my PA to arrive in post... Does this regimen cause an initial breakout?? Or am i getting spots because this is not working for me?
If i add PA how much dosage?
Regards,
Maj
Hi,
I recieved my PA today, just a few questions.
Morning I take 1 450mg pantethine With breakfast, with lunch and then 1 in evening. Inbetween the doses can I take 2 500mg PA? In total 2gm of PA. Will this cause any side effects? Do I need bcomplex?
Or should I start off with taking 1gram then pick up to 2??
Regards,
Maj
Sorry just abit of confusion..
I am taking pantethenic acid which says its from calcium pantothenate.. Is that ok?
Also can i stick to 3 x 450mg of pantethine a day? Or should i reduce this to 2 a day and take 2 grams of PA?
Regards,
Maj
Hi,
If it takes 10g of PA to cure acne why is it recommended to take 900mg of pantethine? And not 10g?
What is 900mg equivalent to PA? And why such a less dose? Although PA breaks down into Pantethine would it not make sence to keep the dose at the same level as it is only a less step in the pathway but not less in dose??
Regards,
Maj
Hi,
Another question sorry.
How long do I need to stay on the following dose;
2 x 450mg Pantethine
2g of PA
I havent seen any improvements yet. I have added b5 and it has only been 4 days but it has been 10 days since I have been on PA but my spots dont seem to be getting any less. ( i have mild acne).
Am I the unlucky one who this does not work for. I guess accutane may be my only hope but I really really do not want to take that.
Regards,
Maj
How long do i need to be on this dose or should i increase?
What is panthenol cream?
Hello i have been reading your threads and am very impressed with your findings well done! I have used PA(B5) on its own before with great success but the second time i used it it did not work(Maybe the pills were poor quality) anyway my question is do you think i should start with the pantethine (900mg) daily or else the 'Co-enzyme A' tabs. I know the co enzyme A tablets have pantethine in them at 1000mg and a host of other ingredients. Not sure where to start? any feedback be great thank you very much
Thank You i'll let u know how i get on
Hi,
I have seen a slight improvement since the last time I posted on here but I am still not getting the desired results as I still have spots.
I am currently taking 2 x 450mg Pantethine
3g PA.
I started off with 2 grams of PA now upto 3. I was wondering can I Increase this dosage upto 4g of PA? As I feel that maybe my body needs more PA and that is why my spots are not clearing.
Thanks
Regards,
Maj
Hi,
I have had taken your adivce and started taking one extra capsule of Pantethine. In total I was taking 3 x 450 split through out the day and I was also taking 3g Of Panthenic Acid.
I have seen no difference at all. If I was to lower the dose of Pantethine to 2 x 450 and up the dose of Pantenthenic Acid to 5g split in between my day. So 1 Pantenthine in morning then at lunch 2.5g of PA, then for Dinner 2.5g of PA and before I go to bed 1 capsule of Pantethine.
Will this dose be harmful to my body?? Will I need to take b complex?? or should I just give up on b5? Id say it has been a little over 2 weeks.
Regards,
Maj
Where do i get this cream from?
I can only find d panthenol cream or b3 panthenol cream are they the same?
Hi ive been doing the Panthetine(900mg) for over a week now and my skin has cleared up 99% but strangely my skin is still real oily(even could be oilier)so its like the oil coming out is clean.. Should i add more Pathethine or just give it more time to work? Thank you
Hi is it the baby cream Penaten? http://www.amazon.com/Penaten-Cream-Cr%C3%A8me-Lar
I'm sorry but i know creams are not going to stop my oily skin it needs to be healed from the inside
would it be ok to take coenzyme A with this penaten cream?
Hi Elqalataway,
I have just received the Penaten cream, Do i apply it all over my face or just on oily parts of my face or on acne prone parts of my face, Thank you for your help hope this works to reduce oil and sorry do i use morning and night or just night time? Thanks again
Thank you i will give it a week or two and let u know how i get on thank you for the quick responses means alot
Hi. I can't find this Penaten cream in my country but i have an alternative. It is called Bepanthen (it contains 5% dexpantenol). What do you think? Is it a good replacement for Penaten cream?
Thanks for your answer. I already bought this cream. It contains: aqua, panthenol 5%, isopropyl myristate, cetyl alcohol, stearyl alcohol, propylene glycol, lanolin, potassium cetyl phosphate, pantolacton, phenoxyethanol, potassium hydroxide. I read the intructions and it says that this cream is greasy, suitable for dry skin. I'm in a dilemma because I have oily skin and this combination (my face + bepanthen) can have comedogenic effect. Any advice please?
Thanks. One last question. I understand this kind of cream prevents acne but is it effective on active spots? Also is it active on blackheads, whiteheads?
Just to let you know 4 Panthitne a day(1800mg) is not working still getting spots and oily skin. Moving to six(2700mg)for a few weeks then giving up if no difference
Darragh but what about the cream? Did you get any results?
The cream is way too thick to use i tryed it one night and does not properly absorb into the skin, it is not made for the face, I could use it at night but not a chance in the morning way to thick.. I believe myself creams are not the answer, I dont see how a cream can stop your skin from producing oil, I started 6 tabs(450mg) yesterday i'll give it a few weeks but im optimistic, dryer lips is all i can feel at the moment. Are u using the cream any results?
I'm using Bepanthen and I saw this cream has other ingredients than Penaten (beside 5% dexpanthenol). But it is also a geasy cream. Until now I used it only for my back in combination with Brevoxyl (4% bpo). I'm applying Brevoxyl to kill p.acnes and after 20-30 minutes I'm applying Bepanthen. After 5 days I can say I really see a difference. I'm not seeing new zits forming but i have many marks from previous ones (i'm having bacne for years now). It;s a good result for only 5 days of treatment and I will continue at least 1-2 months with it.
Mr. Elqalatawy what is your oppinion about niacinamide (niacin, B3 vitamin) cream in treating acne?













Mat 3 years ago
Does this really work? why we did not hear about it before? is it safe?