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Coenzyme A Supplement - The Ultimate Solution of Acne

Updated on April 5, 2012

Coenzyme A supplement can be used to cure acne. In this hub Causes of Acne, we said that the real cause is that the skin stores extra unmetabolized fat in the oil glands present in the skin. We have said also that the amount of fat stored in the skin oil glands (whiteheads, blackheads, pimples), is increased when the body is disposed to synthesize more important fatty molecules like, steroidal hormones, concluding that boosting fat metabolism will clear acne, since the body will convert excess fat stored in the sebaceous glands into energy.

We suggested use of the supplements, Pantothenic acid PLUS L-Cysteine in this hub The B5 New Acne Cure , or use of the supplement, Pantethine alone in this hub Acne Cure Guarantee : Coenzyme A - Pantethine , and the end product of all of these supplements is production of Coenzyme A, which is the starting material of oxidation of fat to produce energy.

Role of Coenzyme A in Fat Metabolism :

Without Coenzyme A, aerobic organisms that depends on Oxygen would not be able to live on planet earth. Acetyl-Coenzyme A is the starting material of the oxygen dependent energy house (mitochondria), that produces energy from carbohydrates,protein and fat, after they all converted into this molecule. Acetyl Coenzyme A is also the starting material of the synthesis of fat molecules, including steroidal hormones. As we can see Coenzyme A is distributed between the cytoplasm and mitochondria (the kitchen and the stove) .

Coenzyme A is used in the primary stages of synthesis of cholesterol (the starting material of steroidal hormones) in cytoplasm, it is recycled only 3 times. However,to produce energy from fatty acids in the mitochondria , Coenzyme A is involved in a sophisticated system to transport and oxidize them. They are recycled about 30 times or more according to the carbon chain length of the fatty acid, to oxidize 1 molecule.

The recommended regimen here is aimed at relieving symptoms of acne, it is to be used temporarily and for a short time. Long term use of high doses of these supplements may induce side effects, and some of them may be serious. If you plan to use them for a long period consult your doctor.

Coenzyme A and Acne



During childhood, growth hormone masters the metabolism to extract energy from fat so that it can spare protein and carbohydrates. After puberty, the body starts to make sex hormones.

Biosynthesis of sex hormones starts with cholesterol, and the body has to synthesize it. It now synthesizes about 50-75 of cholesterol in the body, in the liver, intestines, adrenal glands and gonads. Actually, there are reversible cholesterol plaques on the blood vessels of children starting at the age of 10 years.

This lipid synthesis activity requires large amounts of Coenzyme A to be present in the CYTOPLASM, and this utilizes more of its precursors (Vitamin B5 and Cysteine), at the expense of the amounts of these precursors supplied to the mitochondria.

Sebaceous (oil) glands have no regulatory mechanism and they have open ends (pores), they can secrete the available oil, as the sweat glands can secrete the available sweat. Extra fat can be secreted into pores.


How to Increase Coenzyme A Production

Coenzyme A is composed by the union of 3 molecules, these are Pantothenic acid, L-Cysteine and ATP. Two of these molecules are supplied by food, namely Pantothenic acid (vitamin B5) and the amino acid Cysteine, the third molecule (ATP) is an energy molecule and it is abundant in all the cells.

Dr Lit-Hung Leung was the first to recommend use of Pantothenic acid to treat acne. His regimen was to administer very high doses reaching 1000-1500 times the recommended intake (10 milligrams per day).

I am the one who first recommended adding L-Cysteine to Pantothenic acid, to reduce its dose and side effects with good cure results.

Then I recommended using Pantethine alone as it is the resultant of the union of Cysteine and Pantothenic acid. There are people using it already.
I now recommend intake of Coenzyme A.


What is in Coenzyme A Capsules for Acne:

When Pantothenic acid was used in very high doses to treat acne, it was meant to maintain it in the blood for long time enough to, find its complementary component and the optimal conditions to form Coenzyme A, in the required place.


Coenzyme A capsules claim to provide people with a balanced combination of highly active nutritional components that are used by the cells of the body to support their manufacture and utilization of Coenzyme A. It offers a reliable daily dose of Coenzyme A.

It contains 1000 mg of Pantethine, Pantothenic acid, L-Cysteine, Calcium Pyruvate, Magnesium Malate and L-Acetyl Carnitine (needed for transport of fatty acids across the mitochondrial membrane). The ingredients were all recommended before and now they are present altogether.

The combination is really good and can serve to produce Coenzyme A in the place and amount that are needed by the body to fight acne.

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